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Polyploidization and Cancer

Polyploidization and Cancer

Randy Y.C. Poon

214,84 €
IVA incluido
Disponible
Editorial:
Springer Nature B.V.
Año de edición:
2016
Materia
Medicina: cuestiones generales
ISBN:
9781493951437
214,84 €
IVA incluido
Disponible

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Sobre IBD

Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overviewsubjects relating to polyploidization and cancer.

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Otros libros del autor

  • Polyploidization and Cancer
    Randy Y.C. Poon
    1. Polyploidy, Aneuploidy and the Evolutionof Cancer.................. 1Lauren M. F. Merlo, Li?san Wang, John W. Pepper, Peter S. Rabinovitchand Carlo C. MaleyAbstract.................... 1Introduction................... 1The Tetraploidy to Aneuploidy Progression in Carcinogenesis................. 1Tetraploidy and Aneuploidy in Barrett’s Esophagus................ 2Not All Aneup...