Ekram Guerbeg / Hafedh Abbessi / Mouna Kouira
Librería Samer Atenea
Librería Aciertas (Toledo)
Kálamo Books
Librería Perelló (Valencia)
Librería Elías (Asturias)
Donde los libros
Librería Kolima (Madrid)
Librería Proteo (Málaga)
Early metastatic breast cancer is an aggressive disease. We carried out a retrospective study of 221 cases of stage IV breast cancer to assess the value of local surgery in metastatic breast cancer. One hundred and twenty-nine patients underwent surgery. Healthy margins were obtained in 76.1% of cases. Operated patients had a less advanced T stage (p=0.0001), fewer visceral metastases (p=0.0001) and fewer secondary lesions (p=0.001). After a median follow-up of 36 months, overall survival at 1, 3 and 5 years was better in the operated group (p=0.0001, p=0.002, p=0.019). In the case of isolated bone metastases, operated patients had better overall survival at 1, 3 and 5 years than non-operated patients (p=0.02, p=0.037, p=0.033). Surgical technique had no impact on overall survival or local recurrence. In sano surgery improved 5-year OS (p=0.047). In multivariate analysis, the factors influencing surgical outcome were the presence of visceral metastases, more than 3 metastases and tumour resection limits.
