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Papel funcional dos proteoglicanos no cancro da próstata

Papel funcional dos proteoglicanos no cancro da próstata

Mirzohid Mirzaolimov / Naima Hodzhaeva

90,88 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Medicina: cuestiones generales
ISBN:
9786202328692
90,88 €
IVA incluido
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Sobre IBD

Um dos principais componentes da matriz extracelular do tecido da próstata humana são os proteoglicanos (PGs) - moléculas complexas de proteína-carbohidrato que consistem em proteína da crosta e uma ou mais cadeias de carbohidratos de glicosaminoglicanos (GAGs) ligados a ela. Os proteoglicanos estão envolvidos nas interações célula-célula com proteínas da matriz extracelular, factores de crescimento e quimiocinas e regulam a atividade funcional das células. Através da interação das proteínas da crosta proteoglicanos e glicosaminoglicanos com moléculas da matriz extracelular e moléculas sinalizadoras, os proteoglicanos estão envolvidos na transdução de sinais entre as células e a matriz circundante, o que afecta a motilidade, a adesão, o crescimento e a apoptose e outros processos celulares.

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