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Modulação NO e potencial efeito antiartrítico do rolipram

Modulação NO e potencial efeito antiartrítico do rolipram

Albaker Amnah Farhan / Aledeilah Rawan Deham L. / Romany Thabet

91,03 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Medicina: cuestiones generales
ISBN:
9786209624926
91,03 €
IVA incluido
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Sobre IBD

O rolipram é um inibidor da fosfodiesterase-4 (PDE 4). Está a ser investigado como uma possível alternativa aos antidepressivos atuais (Washtel, 1983; Bobon et al., 1988). Estudos recentes mostram que o rolipram pode ter efeitos antipsicóticos (Maxwell et al., 2004; Kanes et al., 2006). Existem dados contraditórios sobre o papel do óxido nítrico (NO) nas doenças artríticas. No presente trabalho, examinámos se a supressão da produção de NO pela L-NG-monometilarginina (L-NMMA), um inibidor não seletivo da NOS, ou a adição de NO exógeno pela administração de nitroprussiato de sódio (SNP) pode modificar os efeitos do rolipram em ratos com artrite adjuvante.

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Otros libros del autor

  • Modulation NO et effet anti-arthritique possible du rolipram
    Albaker Amnah Farhan / Aledeilah Rawan Deham L. / Romany Thabet
    Le rolipram est un inhibiteur de la phosphodiestérase-4 (PDE 4). Il fait actuellement l’objet de recherches en tant qu’alternative possible aux antidépresseurs actuels (Washtel, 1983 ; Bobon et al., 1988). Des études récentes montrent que le rolipram pourrait avoir des effets antipsychotiques (Maxwell et al., 2004 ; Kanes et al., 2006). Il existe des données contradictoires con...
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  • Modulazione NO ed effetto antiartritico potenziale del rolipram
    Albaker Amnah Farhan / Aledeilah Rawan Deham L. / Romany Thabet
    Il rolipram è un inibitore della fosfodiesterasi-4 (PDE 4). È oggetto di ricerca come possibile alternativa agli attuali antidepressivi (Washtel, 1983; Bobon et al., 1988). Studi recenti dimostrano che il rolipram può avere effetti antipsicotici (Maxwell et al., 2004; Kanes et al., 2006). Esistono dati contrastanti sul ruolo dell’ossido nitrico (NO) nelle malattie artritiche. N...
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  • Modulacja NO i potencjalne działanie przeciwzapalne rolipramu
    Albaker Amnah Farhan / Aledeilah Rawan Deham L. / Romany Thabet
    Rolipram jest inhibitorem fosfodiesterazy-4 (PDE 4). Jest badany jako potencjalna alternatywa dla obecnie stosowanych leków przeciwdepresyjnych (Washtel, 1983; Bobon i in., 1988). Najnowsze badania wskazują, że rolipram może mieć działanie przeciwpsychotyczne (Maxwell i in., 2004; Kanes i in., 2006). Istnieją sprzeczne dane dotyczące roli tlenku azotu (NO) w chorobach stawów. W...
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  • NO-Modulation und potenzielle antiarthritische Wirkung von Rolipram
    Albaker Amnah Farhan / Aledeilah Rawan Deham L. / Romany Thabet
    Rolipram ist ein Phosphodiesterase-4 (PDE 4)-Hemmer. Es wird als mögliche Alternative zu derzeitigen Antidepressiva erforscht (Washtel, 1983; Bobon et al., 1988). Jüngste Studien zeigen, dass Rolipram antipsychotische Wirkungen haben kann (Maxwell et al., 2004; Kanes et al., 2006). Es gibt widersprüchliche Daten über die Rolle von Stickstoffmonoxid (NO) bei arthritischen Erkran...
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