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Influence de l’aflatoxine sur la capacité phagocytaire des neutrophiles et des mo

Influence de l’aflatoxine sur la capacité phagocytaire des neutrophiles et des mo

Rodrigo Henrique Pereira P. Santos / Tatiana Karla Borges

43,69 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Música
ISBN:
9786207608539
43,69 €
IVA incluido
Disponible

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L’aflatoxine est une mycotoxine qui peut être présente dans divers aliments et qui est une source d’empoisonnement pour les humains et les animaux. Les patients atteints d’empoisonnement à l’aflatoxine présentent un degré inquiétant de morbidité et de mortalité. Cependant, on sait peu de choses sur ses effets sur le corps humain et sur la manière dont les processus immunopathologiques sont déclenchés. La phagocytose étant un mécanisme extrêmement important, il est nécessaire de comprendre la possibilité qu’elle provoque une immunodépression chez l’individu. L’objectif de cette étude était d’évaluer l’influence de l’aflatoxine sur la capacité phagocytaire des neutrophiles et des monocytes humains en comptant le nombre de monocytes et de neutrophiles impliqués dans la phagocytose, le nombre moyen de levures Saccharomyces cerevisiae phagocytées et/ou adhérées, l’index phagocytaire et la production de superoxyde. Les résultats ont montré une modulation négative de la phagocytose, due à la fois à une diminution des levures ingérées/adhérées et à un nombre plus faible de cellules impliquées.

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