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I ruoli oncogenici e soppressivi dei microRNA e del Tmor

I ruoli oncogenici e soppressivi dei microRNA e del Tmor

Ammar Ebrahimi / Fakher Rahim / Farideh Ghanbari

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Medicina: cuestiones generales
ISBN:
9786208913571
52,29 €
IVA incluido
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Sobre IBD

Gli acidi micro-ribonucleici (Micro-RNA) sono acidi ribonucleici non codificanti con una lunghezza di 18-25 nucleotidi, evolutivamente conservati. I micro-RNA controllano l’espressione genica post-trascrizionale attraverso la degradazione dell’RNA messaggero (mRNA) o l’inibizione della sua trascrizione. Queste strutture molecolari partecipano al controllo dei processi fisiologici e patologici delle cellule, e molte di esse possono agire come oncogeni o inibitori tumorali; pertanto, le mutazioni in questi open reading frame (ORF) possono portare al cancro. L’identificazione dei micro-RNA e delle loro molecole bersaglio fornisce un orizzonte chiaro per identificare i percorsi legati al cancro; pertanto, questi composti possono essere utilizzati come potenziali biomarcatori per diagnosticare, prevedere e trattare il cancro.

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