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Foreword by John H. Riskind. Preface.-1. Nature of Generalized Anxiety Disorder.-2. Assessment and Diagnosis. DSM-IV-TR: Diagnostic Criteria for Generalized Anxiety Disorder.-3. Conceptual Models. Beck’s Model. Barlow’s Emotion Theory. Cognitive Avoidance Theory of Worry. Riskind’s Model of Looming Vulnerability. The Role of Intolerance of Uncertainty. Metacognitive Model.-4. Psychosocial Treatments for Adults with Generalized Anxiety Disorder. Cognitive Behavioral Therapy (CBT). Metacognitive Therapy. Supportive-Expressive Psychodynamic Therapy. Integrative Psychotherapy. Emotion Regulation Therapy. Acceptance-Based Behavior Therapy.-5. Pharmacotherapy for Generalized Anxiety Disorder. Genetics. Neurobiology. Medications used for Generalized Anxiety Disorder.-6. Special Populations. Children and Adolescents. Clinical Presentation. Assessment and Diagnosis. Psychosocial Treatments. Pharmacological Treatments. Older Adults. Clinical Presentation. Assessment and Diagnosis. Psychosocial Treatments. Pharmacological Treatments.-7. Enigmas and Paradoxes. Prevention. Cultural Considerations. Treatment Resistant Generalized Anxiety Disorder.-8. Future Directions and Recommendations.-Final Remarks.Appendix A: Assessment Tools for Adults and Older Adults. Appendix B: Assessment Tools for Children and Adolescents.