Die Rolle von Biomarkern im Speichel bei Parodontalerkrankungen

Die Rolle von Biomarkern im Speichel bei Parodontalerkrankungen

Anamika Sharma / Deepa D. / Mona Dagar

88,32 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786630525526
88,32 €
IVA incluido
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Sobre IBD

Parodontitis ist eine entzündliche Erkrankung des Zahnhalteapparats. Aus den geschädigten Zellen des parodontalen Gewebes werden zunehmend intrazelluläre Enzyme in die Zahnfleischspaltenflüssigkeit und den Speichel freigesetzt. Die Bestimmung von Biomarkern für das Screening und die Vorhersage des frühen Krankheitsbeginns (prognostische Tests) oder zur Beurteilung der Krankheitsaktivität und der Wirksamkeit der Therapie stellt eine große Herausforderung dar. Zu den verschiedenen Enzymen, die für die Frühdiagnose von Parodontalerkrankungen untersucht wurden, gehören Aspartat- und Alaninaminotransferasen (AST, ALT), Laktatdehydrogenase (LDH), Kreatinkinase (CK), alkalische und saure Phosphatase (ALP, ACP) sowie Gamma-Glutamyltransferase (GGT) und Myeloperoxidase (MPO). Es wurde festgestellt, dass die Aktivitäten der Enzyme CK, LDH, AST, ALT, GGT, ALP, ACP und MPO bei Parodontalerkrankungen erhöht sind. Daher wurde versucht, den diagnostischen Wert von Speichelenzymen bei der Diagnose und dem Verlauf von Parodontalerkrankungen zu untersuchen.

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