Demenze degenerative

Demenze degenerative

Fatma HAMZA / Hend Hachicha / Nouha Farhat

119,76 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Medicina: cuestiones generales
ISBN:
9786208972486
119,76 €
IVA incluido
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Abbiamo reclutato 40 pazienti (16 uomini e 24 donne). L’età media di questi pazienti era di 69±11,78 anni [36-86 anni]. Sulla base dei dati clinici, la diagnosi di malattia di Alzheimer (AD) è stata proposta in 26 pazienti, di degenerazione frontotemporale lobare in 7 pazienti, di demenza a corpi di Lewy (MLD) in 4 casi e 3 pazienti sono stati classificati nel gruppo degli altri tipi di demenza (paralisi sopranucleare progressiva, degenerazione cortico-basale e atrofia multisistemica). Per l’AD, la sensibilità e la specificità dei 3 biomarcatori (Aβ (1-42), T-tau e P-tau) erano rispettivamente dell’82% e del 100%. L’accordo tra i risultati dei test neuropsicologici, l’aspetto scintigrafico e il profilo dei biomarcatori è stato rilevato nel 77,5% dei casi. La scintigrafia miocardica MIBG è stata interessante per la diagnosi di DD, ma nessun singolo test si è rivelato di valore sufficiente per individuare l’eziologia. I dati convergenti di alcuni esami paraclinici sono necessari nelle forme precoci e atipiche, in particolare nei casi di dubbio diagnostico persistente.

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