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Czerniak akralny

Czerniak akralny

Miguel Angel Zúñiga Castillo / Mirian N. Sotto

81,48 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Medicina: cuestiones generales
ISBN:
9786206776475
81,48 €
IVA incluido
Disponible

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Sobre IBD

Czerniak akralny jest rzadkim podtypem czerniaka skóry, który zazwyczaj ma niekorzystny przebieg i jest agresywny. Mechanizmy patogenetyczne związane z tym przebiegiem klinicznym nie są w pełni poznane. Obecnie badania literaturowe koncentrują się na mechanizmach unikania odpowiedzi immunologicznej związanych z mikrośrodowiskiem czerniaka, ponieważ mogą one hamować odpowiedź immunologiczną przeciwnowotworową, umożliwiając postęp choroby. Ekspresja ludzkiego antygenu leukocytowego G i interleukiny 10 oraz makrofagi M2 w mikrośrodowisku nowotworowym są strategiami unikania odpowiedzi immunologicznej opracowanymi przez niektóre nowotwory. Czynniki te nie były jednak dotychczas przedmiotem szczegółowych badań w przypadku czerniaka akralnego.

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