Cząsteczki dengi

Cząsteczki dengi

Crislania dos Santos / Sérgio Modesto Vechi

43,46 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786209471919
43,46 €
IVA incluido
Disponible

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Sobre IBD

Denga jest problemem zdrowia publicznego o znaczeniu globalnym i stała się znana jako jedna z najważniejszych arbowirusów dotykających obecnie ludzi, z powracającymi epidemiami w tropikalnych regionach Azji, Afryki i Ameryk. Podejmowane są znaczne wysiłki w zakresie badań nad leczeniem dengi, jednak na rynku nie ma jeszcze dostępnego leku przeciwwirusowego do leczenia tej choroby. Wśród strategii stosowanych w celu opracowania leków przeciwwirusowych przeciwko dengi na szczególną uwagę zasługuje hamowanie kompleksu NS2B/NS3pro. W tym kontekście niniejszy przegląd opisuje dengę i cząsteczki związane z wirusem dengi, takie jak białka wirusowe i ich inhibitory, w szczególności te związane z proteazą NS3 połączoną z jej kofaktorem NS2B (NS2B-NS3pro). Ponadto porównuje się właściwości różnych klas inhibitorów poprzez obliczenie ich deskryptorów molekularnych.

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