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Confronto dell’efficacia analgesica di tramadolo e tapentadolo

Confronto dell’efficacia analgesica di tramadolo e tapentadolo

Abhinav Kumar / Anisha Deb / Harshad Sharma

54,25 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Odontología
ISBN:
9786207904846
54,25 €
IVA incluido
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La chirurgia del terzo molare mandibolare impattato, una procedura odontoiatrica comune, spesso provoca un dolore post-operatorio significativo, che richiede una gestione analgesica efficace. Il tramadolo e il tapentadolo sono due oppioidi frequentemente utilizzati per alleviare il dolore in questo contesto. Questa sintesi confronta la loro efficacia analgesica, gli effetti collaterali e gli esiti per il paziente nella gestione del dolore postoperatorio dopo questo specifico intervento.Il tramadolo, un analgesico oppioide sintetico ad azione centrale, agisce principalmente legandosi al recettore μ-opioide e inibendo la ricaptazione di noradrenalina e serotonina. Questo duplice meccanismo contribuisce ai suoi effetti analgesici, ma comporta anche un complesso profilo di effetti collaterali.Anche il tapentadolo, un analgesico più recente, agisce sul recettore μ-opioide, ma con una maggiore inibizione della ricaptazione della noradrenalina. Si ipotizza che questo doppio meccanismo semplificato offra un efficace sollievo dal dolore con un profilo di effetti collaterali potenzialmente migliore rispetto al tramadolo.

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