Complexos metálicos de base de Schiff

Complexos metálicos de base de Schiff

Arun T / Kamalesu S / Subramanian S

55,28 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
ISBN:
9786208086800
55,28 €
IVA incluido
Disponible

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Sobre IBD

As bases de Schiff estão entre os ligandos mais importantes devido à sua capacidade quelante e às suas diversas aplicações nos domínios medicinal e farmacológico. Nos últimos anos, os investigadores têm-se debruçado extensivamente sobre a química de coordenação e a reatividade dos ligandos de bases de Schiff. A coordenação de ligandos de base de Schiff com iões metálicos é particularmente interessante porque estes ligandos demonstraram propriedades biológicas melhoradas após metalação. É bem conhecido que os átomos dadores de azoto e oxigénio nos ligandos de base de Schiff desempenham um papel decisivo na coordenação de metais nos locais activos de numerosas metalobiomoléculas. A combinação de bases de Schiff com iões metálicos em complexos metálicos tem demonstrado actividades biológicas frutuosas, incluindo propriedades antitumorais, anti-amoébicas, antimicrobianas e anti-inflamatórias. Os complexos de metais de transição de bases de Schiff exibem diferentes estados de oxidação e podem interagir com várias biomoléculas carregadas negativamente, tornando este um campo sempre verde na química bioinorgânica.

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Otros libros del autor

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