Complexes métalliques dans les systèmes biologiques

Complexes métalliques dans les systèmes biologiques

Bhupesh S. Bhatt / Keyur D. Bhatt / M. N. Patel

74,57 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786209961250
74,57 €
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Sobre IBD

Dans le but de concevoir des métallonucléases artificielles et des molécules à vocation thérapeutique (antibactériennes et antitumorales), nous avons prévu de synthétiser des complexes métalliques à base d’ions d’or et de cuivre, puis nous avons testé leurs diverses activités biologiques, telles que l’interaction avec l’ADN, l’activité mimétique de la SOD, ainsi que leurs activités cytotoxiques et antibactériennes. En tant que médicaments, ces complexes agissent de deux manières : certains utilisent un processus appelé chimie redox pour voler des électrons aux liaisons qui maintiennent les molécules cibles ensemble. D’autres utilisent l’hydrolyse, ce qui signifie qu’ils brisent la barrière chimique imperméable de la cible, de sorte que l’eau naturellement présente dans une cellule dissout la cible.

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