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Cobre e esteatose hepática não alcoólica

Cobre e esteatose hepática não alcoólica

Dana Jallouli

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Medicina: cuestiones generales
ISBN:
9786208492540
65,49 €
IVA incluido
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Sobre IBD

A doença hepática gorda não alcoólica (NAFLD) é reconhecida como a principal causa de doença hepática. Estudos recentes encontraram uma associação entre a deficiência de cobre e as caraterísticas patológicas da NAFLD. O nosso objetivo foi comparar as concentrações séricas de cobre em doentes com NAFLD e em controlos e estabelecer a relação com as caraterísticas biológicas e os valores de esteatose e fibrose na NAFLD. Este foi um estudo caso-controlo de doentes seguidos por NAFLD. Os controlos foram emparelhados com os doentes de acordo com a idade e o sexo. As análises biológicas foram efectuadas no Laboratório de Bioquímica do Hospital Universitário Habib Bourguiba em Sfax. Calculámos as pontuações de esteatose (Fatty Liver Index (FLI) e NAFLD Liver Fat Score (NAFLD LFS)) e as pontuações de fibrose (NAFLD fibrosis score (NFS score) e fibrosis-4 score (FIB-4)) para os doentes com NAFLD.

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