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Calcitonin Gene-Related Peptide (CGRP) Mechanisms

Calcitonin Gene-Related Peptide (CGRP) Mechanisms

 

135,97 €
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Editorial:
Springer Nature B.V.
Año de edición:
2020
Materia
Neurología y neurofisiología clínicas
ISBN:
9783030214562
135,97 €
IVA incluido
Disponible

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Sobre IBD

This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine.  The various chapters address the origin, localization and function of CGRP and its receptor in the peripheral nervous system, in the cardiovascular system, and in other tissues and organs. Further attention is paid to the drug discovery pathway where recent findings show the beneficial effect of small molecule antagonists of the CGRP receptors for the relief of the migraine attack and of monoclonal antibodies against CGRP or the CGRP receptor for migraine prevention. 

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