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Badania syntetyczne glikozylohydrazyno karbotioamidów

Badania syntetyczne glikozylohydrazyno karbotioamidów

Anvita Mangte / Riddhi Nayak

92,32 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Química
ISBN:
9786200753472
92,32 €
IVA incluido
Disponible

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Ze względu na zastosowania N-glikozylowanych związków w chemii medycznej i na wiele innych sposobów, w niniejszym artykule opisano syntezę nowych glikozylohydrazyno karbotioamidów. Nowe N-glikozylohydrazyno karbotioamidy zostały zsyntetyzowane poprzez kondensację per-O-acetylo glikozylo izotiocyjanianu z różnymi aromatycznymi hydrazydami. Przedstawiony protokół obejmuje prostą metodę izolacji z umiarkowaną do dobrej wydajnością w łagodnych warunkach. Potwierdzenie nowo przygotowanych związków przeprowadzono za pomocą badań IR, 1HNMR i widm masowych. Specyficzna rotacja tytułowych związków została określona za pomocą badania polarymetrycznego. Wszystkie nowo zsyntetyzowane N-glikozylohydrazyno karbotioamidy wykazują umiarkowaną do dobrej aktywność przeciwdrobnoustrojową wobec różnych patogenów.

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