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Badania fitochemiczne gatunków z rodzaju Goniothalamus

Badania fitochemiczne gatunków z rodzaju Goniothalamus

Fasihuddin Ahmad / Lim Li Fang / Mui Hung Wong

73,52 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Química
ISBN:
9786209870422
73,52 €
IVA incluido
Disponible

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Goniothalamus uvarioides i Goniothalamus velutinus, należące do rodziny Annonaceae, są stosowane w medycynie tradycyjnej w leczeniu zawrotów głowy, urazów, biegunki, jako środek afrodyzjakalny, przy bólach ciała, przeziębieniu, bólach brzucha, obrzękach, bólach głowy, zatruciach pokarmowych, a także w celu utrzymania zdrowia oraz jako środek odstraszający komary. Przeprowadzono badania fitochemiczne G. uvarioides i G. velutinus. Wyizolowano dwa alkaloidy, jeden styryllakton (styrylhydropyron) oraz dwa flawonoidy. Związki te scharakteryzowano za pomocą analizy spektroskopowej, metod chemicznych oraz poprzez porównanie z opublikowanymi danymi. Zidentyfikowanymi związkami były velutinum, aristolaktam-BII z G. velutinus oraz pinocembryna, goniotalamina, a także 5,7,4’-trihydroksyflawanon (naringenina) z G. uvarioides. Związek S4 wykazał LD50 poniżej 100 ppm, podczas gdy związek S5 wykazał LD50 poniżej 10 ppm w stosunku do Artemia salina. Ponadto związek S5 wykazał silną aktywność przeciwbakteryjną wobec bakterii Gram-dodatnich badanych w ramach badania.

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