ASTROGLIOSIS AND CHANNEL FUNCTION

ASTROGLIOSIS AND CHANNEL FUNCTION

JOHN V. ZIMMERMAN

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Editorial:
mujeeb publishers
Año de edición:
2024
Materia
Neurología y neurofisiología clínicas
ISBN:
9785215198674
25,46 €
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Astrogliosis is a hallmark of central nervous system (CNS) neuroinflammatory disorders such as multiple sclerosis (MS). Astrocytes can playboth beneficial and detrimental roles in response to neuroinflammation, thus a detailed understanding of the underlying molecular mechanisms governingastrogliosis might facilitate the development of therapeutic targets. While astrocytes do not express voltage-gated sodium channel (VGSC) Nav1.5 innonpathological human brain, they exhibit robust upregulation of Navi .5 within acute and chronic MS lesions

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