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Assorbimento orale delle nanoparticelle rispetto alla forma ordinaria dell’ossido di ferro

Assorbimento orale delle nanoparticelle rispetto alla forma ordinaria dell’ossido di ferro

Goudarz Sadeghi Hashjin / Mohammad kazem Koohi / Reyhaneh Kheiri

43,15 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Psicología
ISBN:
9786209256073
43,15 €
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Sobre IBD

Una volta assorbite, le nanoparticelle dovrebbero agire allo stesso modo dei prodotti tradizionali. Tuttavia, il processo di assorbimento non dovrebbe essere identico a quello delle forme tradizionali, poiché le loro diverse caratteristiche fisico-chimiche nei fluidi gastrointestinali potrebbero interagire con i tempi di svuotamento gastrico e intestinale. Ciò potrebbe a sua volta influire sul tempo necessario per raggiungere la concentrazione massima nel sangue e sulle concentrazioni massime raggiunte. Lo scopo del presente studio era quello di determinare le concentrazioni ematiche di ferro dopo la somministrazione orale di nanoparticelle di ossido di ferro. Come modello sperimentale è stato utilizzato il coniglio, poiché le dimensioni dell’animale consentivano il prelievo seriale di sangue. Si tratta solo di un’iniziativa volta a incoraggiare i ricercatori a studiare la cinetica dei nanoprodotti, poiché le differenze rispetto alle sostanze comuni possono influire sugli effetti terapeutici e tossici delle sostanze utilizzate in medicina e biologia.

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