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Approfondimenti strutturali e antimicrobici sugli idrazoni tiofenici

Approfondimenti strutturali e antimicrobici sugli idrazoni tiofenici

Ami Y. Patel / Viral A. Doshi

77,50 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Química
ISBN:
9786209053122
77,50 €
IVA incluido
Disponible

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L’emergenza globale di ceppi microbici resistenti ai farmaci ha intensificato la ricerca di nuove entità chimiche con potenti proprietà antimicrobiche. In questo contesto, i composti eterociclici hanno attirato una notevole attenzione e gli scaffold a base di tiofene sono emersi come candidati promettenti grazie alla loro versatilità strutturale e all’ampia attività biologica. Tra i vari derivati funzionalizzati, gli idrazidi-idrazoni del tiofene hanno mostrato un notevole potenziale farmacologico, in particolare come agenti antimicrobici.Questo libro, Structural and Antimicrobial Insights into Thiophene Hydrazones, è un resoconto completo della sintesi, dell’elucidazione strutturale e della valutazione biologica di una nuova serie di derivati del tiofene. Il lavoro è il culmine di una rigorosa ricerca sperimentale, che combina la sintesi organica classica con le moderne tecniche spettroscopiche e microbiologiche. I derivati presentati in questo libro sono stati meticolosamente caratterizzati utilizzando la spettroscopia IR, NMR e CMR, e le loro attività antibatteriche e antimicotiche sono state sistematicamente valutate attraverso saggi MIC (Concentrazione Minima Inibitoria).

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