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Applications of Antisense Therapies to Restenosis

Applications of Antisense Therapies to Restenosis

LeRoy E. Rabbani

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Editorial:
Springer Nature B.V.
Año de edición:
2011
Materia
Medicina cardiovascular
ISBN:
9781461551843
48,29 €
IVA incluido
Disponible

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Sobre IBD

1 Restenosis: The Clinical Problem.- 2 The Pathobiology of Restenosis. A Paradigm from Clinical and Experimental Studies.- 3 Coronary Repair and Restenosis Cellular Basis for Antisense Approaches.- 4 Vascular Smooth Muscle Cell Biology and Restenosis.- 5 Vascular Antisense Therapy Directed Against c-myc, c-myb, and PCNA.- 6 Phosphorothioate Oligodeoxynucleotides as Inhibitors of gene Expression: Antisenseand Non-Antisense Effects.- 7 Molecular Therapies for Vascular Disease: Altering the Balance Between Cell growth and Cell Death.- 8 Oligonucleotides Containing the G-Quartet Sequence Motif.- 9 Non-G-Quartet, Non-Sequence Specific Antirestenotic Effects of Phosphorothioate Oligodeoxynucleotides.- 10 Local Delivery of Antirestenotic Drugs.- 11 Critical Considerations and Future Directions.

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  • Applications of Antisense Therapies to Restenosis
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    Restenosis, the proliferation of smooth muscle cells (SMC) that line blood vessels, often follows angioplasty. Despite advances in cardiology, restenosis continues to affect up to 40% of the over 500,000 patients who undergo angioplasty each year. Applications of Antisense Therapies to Restenosis is the first volume to address the potential of u...