LIBROS DEL AUTOR: youcef m rustum

5 resultados para LIBROS DEL AUTOR: youcef m rustum

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  • Novel Approaches to Selective Treatments of Human Solid Tumors
    Youcef M. Rustum
    The therapeutic efficacy of FUra has been attributed to its incorporation into cellular RNA and, to its inhibition of thymidylate synthase, leading to potent inhibition of DNA synthesis and DNA damage. Studies of cell lines in vitro and model systems in vivo have demonstrated that although mechanisms of sensitivity and resistance to FUra are multifact...
    Disponible

    68,19 €

  • Novel Approaches to Selective Treatments of Human Solid Tumors
    Youcef M. Rustum
    Fluoropyrimidine Metabolism and Mechanism of Action.- 5-Fluoro-2?-Deoxyuridine: Role of Schedule in its Therapeutic Efficacy.- Comparison of Continuous Infusions and Bolus Injections of 5- Fluorouracil with or without Leucovorin: Implications for Inhibition of Thymidylate Synthase.- Critical Questions for the Future Direction of FU/LV.- Cellular Interactions Between the Natural...
    Disponible

    49,75 €

  • Fluoropyrimidines in Cancer Therapy
    Youcef M. Rustum
    Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The aut...
    Disponible

    148,14 €

  • Fluoropyrimidines in Cancer Therapy
    Randy M. Leffingwell / Youcef M. Rustum
    Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The aut...
    Disponible

    210,14 €

  • Novel Approaches to Selective Treatments of Human Solid Tumors
    Youcef M. Rustum
    Fluoropyrimidine Metabolism and Mechanism of Action.- 5-Fluoro-2?-Deoxyuridine: Role of Schedule in its Therapeutic Efficacy.- Comparison of Continuous Infusions and Bolus Injections of 5- Fluorouracil with or without Leucovorin: Implications for Inhibition of Thymidylate Synthase.- Critical Questions for the Future Direction of FU/LV.- Cellular Interactions Between the Natural...
    Disponible

    122,84 €