LIBROS DEL AUTOR: subhendu basu

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  • Somatic Hypermutation in Peyers Patch Germinal Centers and the Gut Environment
    Subhendu Basu
    Germinal center (GC) reaction and somatic mutation in the spleen in response to protein antigens is absolutely dependent on help from antigen specific CD4+ T lymphocytes and stimulation of B cells via the CD19 co-receptor. However, the absence of CD4 T cell help apparently does not abrogate the GC formation in the Peyers patch. The present study makes use of normal, CD4-null an...
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