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LIBROS DEL AUTOR: sophia chara

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Designing Innovative HDAC Protein Inbitors Through 3D QSAR Modeling and Computational Evaluation Methods

Sophia Chara

The balance of reversible acetylation and deacetylation of histones is critical to the regulation of chromatin structure, and it directly affects gene expression in eukaryotic organisms. Two classes of enzymes modulate histone acetylation, histone acetyl transferases (HATs) and histone deacetylases (HDACs), which catalyze the addition and removal, re...

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