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LIBROS DEL AUTOR: gabriele imre

1 resultados para LIBROS DEL AUTOR: gabriele imre

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Anti-apoptotic and Pro-inflammatory Signaling in Cancer Cells - Status and Modulation by Chemotherapeutic Drugs

Gabriele Imre

The transcription factor nuclear factor kappa-B (NFkB) plays a pivotal role in the immune response but is also involved in cancer development and progression. In unstimulated cells NFkB is kept inactive in the cytoplasm by inhibitor of NFkB (IkB) proteins. Dysregulation of the pathway or activation of NFkB by chemotherapeutic agents may lead to cancer progression or drug resis...

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