LIBROS DEL AUTOR: ben a oostra

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  • Trinucleotide Diseases and Instability
    Ben A. Oostra
    Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex­ pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unst...
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