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Bacilos Gram-negativos isolados do ambiente hospitalar

Bacilos Gram-negativos isolados do ambiente hospitalar

Abdelbasset Mechai / Manel Debabza

131,26 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Microbiología (no médica)
ISBN:
9786207044160
131,26 €
IVA incluido
Disponible

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Neste estudo, foram isoladas 306 estirpes de bacilos Gram-negativos (BGN) do ambiente hospitalar, 74,51% das quais eram enterobactérias. Os testes de suscetibilidade aos antibióticos revelaram resistência a várias famílias de antibióticos, particularmente aos antibióticos β-lactâmicos, embora o imipenem, os aminoglicosídeos e as fluoroquinolonas tenham sido notavelmente eficazes. Foram utilizados testes de deteção de beta-lactamases de espetro alargado (ESBL) para caraterizar 114 estirpes de Enterobacteriaceae produtoras de ESBL (EBLSE). A análise dos perfis plasmídicos mostrou que as estirpes multirresistentes contêm 1 a 4 plasmídeos de 1Kb a 170Kb. As experiências de conjugação mostraram a co-transferência da resistência à gentamicina e ao cotrimoxazol para plasmídeos de 10Kb, 20Kb, 125Kb ou 165Kb. A PCR das estirpes transconjugantes detectou os genes bla CTX-M-1, bla TEM e bla SHV, bem como os genes qnrB. Este estudo mostra que o ambiente hospitalar está contaminado por BGN multirresistentes, em particular EBLSE, e que pode ser uma fonte potencial de epidemias, o que leva a que sejam feitas recomendações nas unidades de saúde.

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Otros libros del autor

  • Gram-negative bacilli isolated from the hospital environment
    Abdelbasset Mechai / Manel Debabza
    In this study, 306 Gram-negative bacilli (GNB) strains were isolated from the hospital environment, 74.51% of them enterobacteria. Antibiotic susceptibility testing revealed resistance to various families of antibiotics, in particular β-lactam antibiotics, although imipenem, aminoglycosides and fluoroquinolones were remarkably effective. Extended-spectrum beta-lactamase (ESBL) ...
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    Bei dieser Untersuchung wurden 306 Stämme gramnegativer Bazillen (BGN) aus der Krankenhausumgebung isoliert, darunter 74,51% Enterobakterien. Die Untersuchung der Antibiotikaempfindlichkeit zeigte eine Resistenz gegen verschiedene Familien, insbesondere gegen β-Laktam-Antibiotika, wobei jedoch Imipenem, Aminoglykoside und Fluorchinolone bemerkenswert wirksam waren. Durch Tests ...
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  • Bacilli Gram-negativi isolati dall’ambiente ospedaliero
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    In questo studio sono stati isolati 306 ceppi di bacilli Gram-negativi (GNB) dall’ambiente ospedaliero, il 74,51% dei quali erano enterobatteri. I test di suscettibilità agli antibiotici hanno mostrato una resistenza a diverse famiglie di antibiotici, in particolare agli antibiotici β-lattamici, sebbene imipenem, aminoglicosidi e fluorochinoloni siano risultati notevolmente eff...
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